13:30 - 14:00
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Manuscript ID. 0809
Paper No. 2019-FRI-S0603-I001
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Invited Speaker: Jennifer Barton
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Multi-Modality Optical Imaging Salpingoscope for Early Cancer Detection
Jennifer Barton
Advanced optical imaging techniques such as fluorescence imaging (FI), optical coherence tomography (OCT), and multiphoton microscopy (MPM) can be used for early detection of cancer in a miniature endoscopic system.
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14:00 - 14:15
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Manuscript ID. 0518
Paper No. 2019-FRI-S0603-O001
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Chuan-Bor Chueh
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Wide Field-of-view Tissue Architectural Scanner with a Long-wavelength Swept Source Optical Coherence Tomography Imaging System
Chuan-Bor Chueh;Ching-Yu Wang;Ting-Yen Tsai;Yin-Peng Huang;Teng-Chieh Chang;Ting-Hao Chen;You-Nan Tsai;Yi-Ping Hung;Hsiang-Chieh Lee
e have developed a high speed, and long-wavelength swept-source optical coherence tomography (SS-OCT) imaging system with a 1.7 µm wavelength-swept laser. With a specifically designed fiber-optic scanning microscope where two objectives with different magnification (5X and 10X), it allows multiscale and wide field-of-view imaging of the imaging tissue specimens.
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14:15 - 14:30
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Manuscript ID. 0330
Paper No. 2019-FRI-S0603-O002
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Yao-Hsuan Lai
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Two-Dimensional Photonic Crystal Biosensors Coupled with Surface Plasmonic Resonance
Yao-Hsuan Lai;Yung-Tsan Chen;Jian-Jang Huang
We demonstrated a compact two-dimensional hexagonal photonic crystal biosensor with thin gold film coating. Surface plasmon polariton on the metal structure and phase matching of optical wave with the photonic crystal are considered when analyzing light-biomaterial interaction, which helps detecting small variations of the refractive index on the sensor surface.
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14:30 - 14:45
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Manuscript ID. 0629
Paper No. 2019-FRI-S0603-O003
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Shih Chun Yen
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Enhancement of the Limit of Protein Detection Based on Polymer-Stabilized Liquid Crystals
Shih Chun Yen;Wei Lee
We propose to apply polymer-stabilized liquid crystals (PSLCs) as the sensing element for protein detection. After irradiating ultraviolet light to perform the photopolymerization process, our results indicate that the limit of detection can be promoted due to the enhancement of the optical signal, derived from the light scattering.
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14:45 - 15:00
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Manuscript ID. 0520
Paper No. 2019-FRI-S0603-O004
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Sandeep Chakraborty
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A 1.26 µm Cr: Forsterite Laser Based Higher Harmonic Generation Microscopy for Neuropathology
Sandeep Chakraborty;Ming_Jang Chiu;Chi-Kuang Sun
To meet the urgent need of label-free neuropathological diagnostics in clinics, we have demonstrated the capability of a 1.26 µm laser excitation source based simultaneous detection of second and third harmonic generation to provide dual endogenous contrasts for Alzheimer’s disease hallmarks: Aβ plaques and neurofibrillary tangles along with axons/dendrites.
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15:00 - 15:15
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Manuscript ID. 0758
Paper No. 2019-FRI-S0603-O005
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Jia-Hong Lai
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Investigate the Optical Clearing Effects and Mechanisms of Ex Vivo and In Vivo Human Skin with Glycerol Application by Harmonic Generation Microscopy
Jia-Hong Lai;Chi-Kuang Sun
Optical clearing technique has been widely used to enhance the image quality and image depth. However, the optical clearing effects and mechanisms of in vivo human skin remain unclear. In this study, we demonstrate and compare the optical clearing effects of in vivo and ex vivo human skin.
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